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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730901
Species: Homo sapiens
RGD Object: Gene
Symbol: HMOX1
Name: heme oxygenase 1
Acc ID: CHEBI:80828
Term: Gastrodin
Definition: A glycoside that has formula C13H18O7.
Chemical ID: MESH:C045345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HMOX1increases expressionEXP 6480464CTDgastrodin results in increased expression of HMOX1 proteinPMID:26634892
HMOX1multiple interactionsEXP 6480464CTD[gastrodin co-treated with Oleic Acid] results in increased expression of HMOX1 protein; dorsomorphin inhibits the reaction [[gastrodin co-treated with Oleic Acid] results in increased expression of HMOX1 protein]PMID:26634892
HMOX1multiple interactionsISOHmox1 (Mus musculus)6480464CTD[gastrodin co-treated with Dietary Fats] results in increased expression of HMOX1 protein; gastrodin inhibits the reaction [Glutamic Acid results in decreased expression of HMOX1 protein]PMID:26634892 PMID:31698019
HMOX1multiple interactionsISOHmox1 (Rattus norvegicus)6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of HMOX1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of HMOX1 protein]]; [gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of HMOX1 protein]; gastrodin inhibits the reaction [3,3'-iminodipropionitrile results in decreased expression of HMOX1 protein]; Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of HMOX1 protein]]PMID:31468582 PMID:33645131
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