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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344192
Species: Homo sapiens
RGD Object: Gene
Symbol: TNF
Name: tumor necrosis factor
Acc ID: CHEBI:80828
Term: Gastrodin
Definition: A glycoside that has formula C13H18O7.
Chemical ID: MESH:C045345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNFmultiple interactionsEXP 6480464CTDdorsomorphin inhibits the reaction [gastrodin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]]; gastrodin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]PMID:26634892
TNFmultiple interactionsISOTnf (Mus musculus)6480464CTDgastrodin inhibits the reaction [Dietary Fats results in increased expression of TNF mRNA]PMID:26634892
TNFmultiple interactionsISOTnf (Rattus norvegicus)6480464CTDgastrodin inhibits the reaction [3,3'-iminodipropionitrile results in increased expression of TNF protein]; gastrodin inhibits the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased expression of TNF protein]PMID:30790395 PMID:31468582
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