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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552388
Species: Mus musculus
RGD Object: Gene
Symbol: Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Acc ID: CHEBI:7625
Term: nordihydroguaiaretic acid
Definition: A tetrol that is butane which is substituted at positions 2 and 3 by 3,4-dihydroxybenzyl groups. Masoprocol, the meso-form found in the leaves of the creosote bush (Larrea divaricata), is a potent lipoxygenase inhibitor.
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acacadecreases expression ISOAcaca (Rattus norvegicus)329955565RGDNDGA decreases expression of mRNA in liver of high fructose fed rats 
Acacaincreases phosphorylationISOAcaca (Rattus norvegicus)329955565RGDNDGA increases phosphorylation in liver of high fructose fed rats 
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