GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TNF | multiple interactions | EXP | | 6480464 | CTD | cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of NFKBIA protein] | PMID:23970801 | TNF | decreases expression | ISO | Tnf (Mus musculus) | 6480464 | CTD | cyanoginosin LR results in decreased expression of TNF mRNA | PMID:23454832 | TNF | increases expression | ISO | Tnf (Mus musculus) | 6480464 | CTD | cyanoginosin LR results in increased expression of TNF mRNA; cyanoginosin LR results in increased expression of TNF protein | PMID:21684301 PMID:23454832 PMID:26984711 PMID:28189720 PMID:34416350 PMID:35032610 PMID:37342990 | TNF | increases secretion | ISO | Tnf (Rattus norvegicus) | 6480464 | CTD | cyanoginosin LR results in increased secretion of TNF protein | PMID:37467923 | TNF | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | [Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] promotes the reaction [cyanoginosin LR results in increased expression of TNF protein]; cyanoginosin LR inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; cyanoginosin LR promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL6 protein]; Ethidium inhibits the reaction [cyanoginosin LR results in increased expression of TNF mRNA]; NLRP3 protein affects the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] promotes the reaction [cyanoginosin LR results in increased expression of TNF protein]]; sulforaphane inhibits the reaction [cyanoginosin LR results in increased expression of TNF mRNA] | PMID:15712326 PMID:21684301 PMID:23970801 PMID:34416350 PMID:35032610 | | ||||||||||||||||||||||
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