GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl2 | multiple interactions | EXP | | 6480464 | CTD | Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; Metformin inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA] | PMID:25108154 PMID:30551545 PMID:33639173 | Ccl2 | decreases expression | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | Metformin results in decreased expression of CCL2 mRNA | PMID:20956498 | Ccl2 | multiple interactions | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | Metformin inhibits the reaction [AGT protein results in increased secretion of CCL2 protein]; Metformin inhibits the reaction [Folic Acid results in increased expression of CCL2 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of CCL2 mRNA] | PMID:26497364 PMID:29380373 PMID:29499335 | | ||||||||||||||||||||||
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