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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2147
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ar
Name: androgen receptor
Acc ID: CHEBI:50815
Term: norgestimate
Definition: A ketoxime that has formula C23H31NO3.
Chemical ID: MESH:C017576
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Araffects localizationISOAR (Homo sapiens)6480464CTDnorgestimate affects the localization of AR proteinPMID:17505938 PMID:28478275
Ardecreases expressionISOAR (Homo sapiens)6480464CTDnorgestimate results in decreased expression of AR mRNAPMID:17505938
Armultiple interactionsISOAR (Homo sapiens)6480464CTDnorgestimate binds to and results in decreased activity of AR protein; norgestimate binds to and results in increased activity of AR proteinPMID:17505938 PMID:28478275
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