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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345007
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP2E1
Name: cytochrome P450 family 2 subfamily E member 1
Acc ID: CHEBI:47217
Term: arsane
Definition: An arsine that has formula 77.94542.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2E1affects expressionEXP 6480464CTDArsenic affects the expression of CYP2E1 mRNAPMID:18414638
CYP2E1decreases activityISOCyp2e1 (Rattus norvegicus)6480464CTDArsenic results in decreased activity of CYP2E1 proteinPMID:19932728
CYP2E1multiple interactionsISOCyp2e1 (Rattus norvegicus)6480464CTDArsenic inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein]PMID:19932728
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