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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61867
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp9
Name: caspase 9
Acc ID: CHEBI:40618
Term: aminoguanidine
Definition: A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Chemical ID: MESH:C004479
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp9multiple interactionsISOCasp9 (Mus musculus)6480464CTDpimagedine inhibits the reaction [Cardiotoxins results in increased cleavage of CASP9 protein]PMID:17786558
Casp9multiple interactionsISOCASP9 (Homo sapiens)6480464CTDpimagedine inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP9 protein]; pimagedine promotes the reaction [chromium hexavalent ion results in increased activity of CASP9 protein]; pimagedine promotes the reaction [sodium bichromate results in increased activity of CASP9 protein]PMID:19556603 PMID:33930484
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