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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1315695
Species: Homo sapiens
RGD Object: Gene
Symbol: AKR1C1
Name: aldo-keto reductase family 1 member C1
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AKR1C1multiple interactionsEXP 6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR1C1 mRNAPMID:29741670 PMID:31738976
AKR1C1decreases expressionISOAkr1c1 (Rattus norvegicus)6480464CTDCadmium Chloride results in decreased expression of AKR1C1 mRNAPMID:25993096
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