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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68645
Species: Mus musculus
RGD Object: Gene
Symbol: Cldn5
Name: claudin 5
Acc ID: CHEBI:34631
Term: chlorpyrifos
Definition: An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.
Chemical ID: MESH:D004390
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cldn5increases expressionEXP 6480464CTDChlorpyrifos results in increased expression of CLDN5 mRNAPMID:34289071 PMID:37019170
Cldn5multiple interactionsEXP 6480464CTDVEGFA protein promotes the reaction [Chlorpyrifos results in increased expression of CLDN5 protein]PMID:37263558
Cldn5affects expressionISOCldn5 (Rattus norvegicus)6480464CTDChlorpyrifos affects the expression of CLDN5 mRNAPMID:22611033
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