GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfkb1 | affects expression | ISO | NFKB1 (Homo sapiens) | 6480464 | CTD | Capsaicin affects the expression of NFKB1 mRNA | PMID:19502594 | Nfkb1 | multiple interactions | ISO | NFKB1 (Homo sapiens) | 6480464 | CTD | [NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]] which results in increased expression of DUSP1 protein; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein] | PMID:22171160 | | ||||||||||||||||||||||
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