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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734256
Species: Mus musculus
RGD Object: Gene
Symbol: Spag4
Name: sperm associated antigen 4
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Spag4increases methylationEXP 6480464CTDbisphenol A results in increased methylation of SPAG4 promoterPMID:27312807
Spag4affects expressionISOSPAG4 (Homo sapiens)6480464CTDbisphenol A affects the expression of SPAG4 mRNAPMID:30903817
Spag4decreases expressionISOSpag4 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of SPAG4 mRNAPMID:25181051
Spag4increases expressionISOSpag4 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of SPAG4 mRNAPMID:34947998
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