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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3786
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc8
Name: ATP binding cassette subfamily C member 8
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc8affects expressionEXP 6480464CTDbisphenol A affects the expression of ABCC8 mRNAPMID:23328667
Abcc8decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ABCC8 mRNAPMID:25181051 PMID:30816183
Abcc8increases expressionEXP 6480464CTDbisphenol A results in increased expression of ABCC8 mRNAPMID:32145629
Abcc8increases methylationEXP 6480464CTDbisphenol A results in increased methylation of ABCC8 genePMID:28505145
Abcc8increases expressionISOAbcc8 (Mus musculus)6480464CTDbisphenol A results in increased expression of ABCC8 mRNAPMID:29161229
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