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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1566408
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lin28a
Name: lin-28 homolog A
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lin28adecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of LIN28A mRNAPMID:25181051
Lin28adecreases expressionISOLIN28A (Homo sapiens)6480464CTDbisphenol A results in decreased expression of LIN28A mRNA; bisphenol A results in decreased expression of LIN28A proteinPMID:31715268 PMID:37567409
Lin28adecreases methylationISOLIN28A (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of LIN28A genePMID:31601247
Lin28aincreases expressionISOLIN28A (Homo sapiens)6480464CTDbisphenol A results in increased expression of LIN28A proteinPMID:37664457
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