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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69445
Species: Mus musculus
RGD Object: Gene
Symbol: Acsl5
Name: acyl-CoA synthetase long-chain family member 5
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acsl5increases expressionEXP 6480464CTDpirinixic acid results in increased expression of ACSL5 mRNAPMID:15375163 PMID:17118139 PMID:18301758 PMID:18467677 PMID:20059764 PMID:20936131 PMID:23811191
Acsl5multiple interactionsEXP 6480464CTDPPARA protein promotes the reaction [pirinixic acid results in increased expression of ACSL5 mRNA]PMID:18467677 PMID:20059764
Acsl5multiple interactionsISOACSL5 (Homo sapiens)6480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ACSL5 mRNAPMID:19710929
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