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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68645
Species: Mus musculus
RGD Object: Gene
Symbol: Cldn5
Name: claudin 5
Acc ID: CHEBI:31767
Term: lead diacetate
Definition: A lead coordination entity in which a central lead(2+) atom is coordinated to two acetate ions.
Chemical ID: MESH:C008261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cldn5multiple interactionsEXP 6480464CTD[lead acetate results in increased abundance of Lead] which results in decreased expression of CLDN5 proteinPMID:31730887
Cldn5decreases expressionISOCLDN5 (Homo sapiens)6480464CTDlead acetate results in decreased expression of CLDN5 proteinPMID:24200059
Cldn5multiple interactionsISOCLDN5 (Homo sapiens)6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lead acetate results in decreased expression of CLDN5 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [lead acetate results in decreased expression of CLDN5 protein]PMID:24200059
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