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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1320575
Species: Homo sapiens
RGD Object: Gene
Symbol: PON2
Name: paraoxonase 2
Acc ID: CHEBI:31767
Term: lead diacetate
Definition: A lead coordination entity in which a central lead(2+) atom is coordinated to two acetate ions.
Chemical ID: MESH:C008261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PON2decreases activityEXP 6480464CTDlead acetate results in decreased activity of PON2 proteinPMID:22271317
PON2increases expressionEXP 6480464CTDlead acetate results in increased expression of PON2 mRNAPMID:22271317
PON2multiple interactionsEXP 6480464CTDCalcium inhibits the reaction [lead acetate results in decreased activity of PON2 protein]PMID:22271317
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