GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HMOX1 | increases expression | EXP | | 6480464 | CTD | cilostazol results in increased expression of HMOX1 mRNA; cilostazol results in increased expression of HMOX1 protein | PMID:20131233 PMID:21660147 | HMOX1 | increases response to substance | EXP | | 6480464 | CTD | HMOX1 results in increased susceptibility to cilostazol | PMID:20131233 | HMOX1 | multiple interactions | EXP | | 6480464 | CTD | copper protoporphyrin IX inhibits the reaction [cilostazol results in increased expression of HMOX1 protein]; HMOX1 mutant form inhibits the reaction [cilostazol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; HMOX1 mutant form inhibits the reaction [cilostazol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; HMOX1 mutant form inhibits the reaction [cilostazol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; HMOX1 protein promotes the reaction [cilostazol results in increased activity of PPARG protein]; NFE2L2 mutant form inhibits the reaction [cilostazol results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [cilostazol results in increased expression of HMOX1 mRNA]; zinc protoporphyrin inhibits the reaction [cilostazol results in increased expression of HMOX1 protein] | PMID:20131233 PMID:21660147 | HMOX1 | increases expression | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | cilostazol results in increased expression of HMOX1 mRNA; cilostazol results in increased expression of HMOX1 protein | PMID:21256160 | HMOX1 | multiple interactions | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | Cilostazol inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 mRNA]; Cilostazol inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]; Cilostazol inhibits the reaction [Nitroprusside results in decreased expression of HMOX1 protein] | PMID:18311796 PMID:32456565 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |