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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1622247
Species: Mus musculus
RGD Object: Gene
Symbol: Epcip
Name: exosomal polycystin 1 interacting protein
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Epcipaffects methylationISOEPCIP (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of EPCIP 5' UTRPMID:27901495
Epcipdecreases methylationISOEPCIP (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of EPCIP 3' UTR; Benzo(a)pyrene results in decreased methylation of EPCIP promoterPMID:27901495
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