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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2482
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp7a1
Name: cytochrome P450 family 7 subfamily A member 1
Acc ID: CHEBI:28865
Term: taurocholic acid
Definition: A bile acid taurine conjugate of cholic acid that usually occurs as the sodium salt of bile in mammals.
Chemical ID: MESH:D013656
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp7a1decreases expressionEXP 6480464CTDTaurocholic Acid results in decreased expression of CYP7A1 mRNAPMID:7832767
Cyp7a1decreases expressionISOCyp7a1 (Mus musculus)6480464CTDTaurocholic Acid results in decreased expression of CYP7A1 mRNAPMID:16284190
Cyp7a1multiple interactionsISOCyp7a1 (Mus musculus)6480464CTDFGFR4 protein affects the reaction [Taurocholic Acid results in decreased expression of CYP7A1 mRNA]; NR1H4 protein affects the reaction [Taurocholic Acid results in decreased expression of CYP7A1 mRNA]PMID:16284190
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