GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bdnf | multiple interactions | EXP | | 6480464 | CTD | [Copper Sulfate results in increased abundance of Copper] which results in increased expression of BDNF protein; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of BDNF protein]; Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of BDNF protein] | PMID:34577062 | Bdnf | affects binding | ISO | BDNF (Homo sapiens) | 6480464 | CTD | Copper binds to BDNF protein modified form | PMID:23135810 | Bdnf | decreases expression | ISO | Bdnf (Mus musculus) | 6480464 | CTD | Copper results in decreased expression of BDNF protein | PMID:34676557 | Bdnf | multiple interactions | ISO | BDNF (Homo sapiens) | 6480464 | CTD | [Chelating Agents binds to Copper] which results in decreased expression of BDNF mRNA; [Disulfiram binds to Copper] which results in increased expression of BDNF mRNA | PMID:24690739 PMID:30911355 | | ||||||||||||||||||||||
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