Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736181
Species: Mus musculus
RGD Object: Gene
Symbol: Glul
Name: glutamate-ammonia ligase
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Glulaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of GLUL mRNAPMID:21570461
Gluldecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of GLUL mRNA; Tetrachlorodibenzodioxin results in decreased expression of GLUL proteinPMID:16960034 PMID:25270620 PMID:38013089
Glulincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of GLUL mRNAPMID:19933214
Glulincreases methylationEXP 6480464CTDTetrachlorodibenzodioxin results in increased methylation of GLUL genePMID:21212295
Glulmultiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of GLUL mRNA; [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in increased methylation of GLUL genePMID:17942748 PMID:21212295
Glulaffects expressionISOGlul (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of GLUL mRNAPMID:34747641
Gluldecreases expressionISOGlul (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of GLUL mRNAPMID:16054898 PMID:16960034 PMID:18796159 PMID:33387578
Go Back to source page   Continue to Ontology report