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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1603705
Species: Homo sapiens
RGD Object: Gene
Symbol: GPRC5A
Name: G protein-coupled receptor class C group 5 member A
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GPRC5Aaffects expressionISOGprc5a (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of GPRC5A mRNAPMID:21570461
GPRC5Aincreases expressionISOGprc5a (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of GPRC5A mRNAPMID:34747641
GPRC5Aincreases expressionISOGprc5a (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of GPRC5A mRNAPMID:19770486 PMID:19933214 PMID:32553695
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