GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bcl6 | affects expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of BCL6 mRNA | PMID:22298810 | Bcl6 | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of BCL6 mRNA | PMID:33387578 | Bcl6 | affects expression | ISO | Bcl6 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of BCL6 mRNA | PMID:21570461 PMID:28922406 | Bcl6 | decreases expression | ISO | BCL6 (Homo sapiens) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of BCL6 mRNA | PMID:26238291 | Bcl6 | decreases expression | ISO | Bcl6 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of BCL6 mRNA | PMID:18684927 PMID:25975270 | Bcl6 | increases expression | ISO | BCL6 (Homo sapiens) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of BCL6 mRNA; Tetrachlorodibenzodioxin results in increased expression of BCL6 protein | PMID:21802500 PMID:27546522 | Bcl6 | increases expression | ISO | Bcl6 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of BCL6 mRNA | PMID:17035482 PMID:24058054 | Bcl6 | multiple interactions | ISO | BCL6 (Homo sapiens) | 6480464 | CTD | 2-chlorodibenzo-4-dioxin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of BCL6 protein]; [Tetrachlorodibenzodioxin results in increased expression of BCL6 protein] which results in decreased expression of CD69 protein; [Tetrachlorodibenzodioxin results in increased expression of BCL6 protein] which results in decreased expression of CD80 protein; AHR affects the reaction [Tetrachlorodibenzodioxin results in increased expression of BCL6 protein]; Tetrachlorodibenzodioxin promotes the reaction [BCL6 protein binds to CD80 enhancer]; Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of BCL6 protein | PMID:25543051 | Bcl6 | multiple interactions | ISO | Bcl6 (Mus musculus) | 6480464 | CTD | [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in increased expression of BCL6 protein | PMID:20348231 | | ||||||||||||||||||||||
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