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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68949
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il13
Name: interleukin 13
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il13multiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased secretion of IL13 protein]PMID:26621445
Il13decreases expressionISOIL13 (Homo sapiens)6480464CTDresveratrol results in decreased expression of IL13 mRNAPMID:23224687
Il13decreases expressionISOIl13 (Mus musculus)6480464CTDresveratrol results in decreased expression of IL13 proteinPMID:22962611 PMID:22986054
Il13decreases response to substanceISOIL13 (Homo sapiens)6480464CTDresveratrol results in decreased susceptibility to IL13 proteinPMID:22254182
Il13decreases secretionISOIL13 (Homo sapiens)6480464CTDresveratrol results in decreased secretion of IL13 proteinPMID:23251493
Il13multiple interactionsISOIL13 (Homo sapiens)6480464CTD[Plant Extracts co-treated with Resveratrol] results in decreased expression of IL13 mRNA; Resveratrol inhibits the reaction [IL13 protein results in increased expression of CCL11 mRNA]; Resveratrol inhibits the reaction [IL13 protein results in increased secretion of CCL11 protein]PMID:22254182 PMID:23557933
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