GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Got1 | increases activity | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased activity of GOT1 protein | PMID:17200984 | Got1 | increases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased expression of GOT1 mRNA; Carbon Tetrachloride results in increased expression of GOT1 protein | PMID:15095147 PMID:16239168 PMID:26862777 PMID:30676168 | Got1 | multiple interactions | EXP | | 6480464 | CTD | Ascorbic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of GOT1 protein]; Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of GOT1 protein]; Ramipril inhibits the reaction [Carbon Tetrachloride results in increased expression of GOT1 protein] | PMID:15095147 PMID:26862777 PMID:30676168 | Got1 | affects expression | ISO | Got1 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride affects the expression of GOT1 mRNA | PMID:31919559 | Got1 | decreases expression | ISO | Got1 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in decreased expression of GOT1 mRNA | PMID:27339419 | Got1 | increases activity | ISO | Got1 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased activity of GOT1 protein | PMID:37573684 | Got1 | increases expression | ISO | Got1 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of GOT1 protein | PMID:37894611 | Got1 | increases secretion | ISO | Got1 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased secretion of GOT1 protein | PMID:25747392 | Got1 | multiple interactions | ISO | Got1 (Mus musculus) | 6480464 | CTD | [Dietary Fats co-treated with Carbon Tetrachloride] results in increased expression of and results in increased secretion of GOT1 protein; alisol B 23-acetate inhibits the reaction [Carbon Tetrachloride results in increased activity of GOT1 protein]; alisol B 23-acetate inhibits the reaction [Carbon Tetrachloride results in increased secretion of GOT1 protein]; alisol B inhibits the reaction [[Dietary Fats co-treated with Carbon Tetrachloride] results in increased expression of and results in increased secretion of GOT1 protein]; Chenodeoxycholic Acid inhibits the reaction [Carbon Tetrachloride results in increased secretion of GOT1 protein]; Colchicine inhibits the reaction [Carbon Tetrachloride results in increased activity of GOT1 protein]; gentian root extract inhibits the reaction [Carbon Tetrachloride results in increased expression of GOT1 protein]; pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate inhibits the reaction [Carbon Tetrachloride results in increased activity of GOT1 protein]] | PMID:25747392 PMID:35745142 PMID:37573684 PMID:37894611 | | ||||||||||||||||||||||
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