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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730901
Species: Homo sapiens
RGD Object: Gene
Symbol: HMOX1
Name: heme oxygenase 1
Acc ID: CHEBI:180664
Term: 4-hydroxy-TEMPO
Definition: A member of the class of aminoxyls that is TEMPO carrying a hydroxy substituent at position 4. It is a radical scavenger which exhibits anti-inflammatory and analgesic properties.
Chemical ID: MESH:C001803
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HMOX1increases expressionISOHmox1 (Rattus norvegicus)6480464CTDtempol results in increased expression of HMOX1 mRNAPMID:12595275
HMOX1multiple interactionsISOHmox1 (Mus musculus)6480464CTD[tempol co-treated with Tobacco Smoke Pollution] results in increased expression of HMOX1 mRNAPMID:32726580
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