GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp2e1 | increases response to substance | EXP | | 6480464 | CTD | CYP2E1 protein results in increased susceptibility to Tetrachloroethylene | PMID:17433522 | Cyp2e1 | decreases response to substance | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | CYP2E1 gene mutant form results in decreased susceptibility to Tetrachloroethylene | PMID:29897530 | Cyp2e1 | increases oxidation | ISO | CYP2E1 (Homo sapiens) | 6480464 | CTD | CYP2E1 protein results in increased oxidation of Tetrachloroethylene | PMID:29897530 | Cyp2e1 | multiple interactions | ISO | CYP2E1 (Homo sapiens) | 6480464 | CTD | [CYP2E1 protein results in increased oxidation of Tetrachloroethylene] which results in increased abundance of Trichloroacetic Acid | PMID:29897530 | | ||||||||||||||||||||||
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