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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1323180
Species: Mus musculus
RGD Object: Gene
Symbol: Tet2
Name: tet methylcytosine dioxygenase 2
Acc ID: CHEBI:17042
Term: tetrachlorohydroquinone
Definition: A tetrachlorobenzene that is 1,2,4,5-tetrachlorobenzene in which the hydrogens at positions 3 and 6 are replaced by hydroxy groups.
Chemical ID: MESH:C044578
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tet2multiple interactionsEXP 6480464CTDTET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased oxidation of 5-Methylcytosine]PMID:24214992
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