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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69219
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh2
Name: aldehyde dehydrogenase 2 family member
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh2increases expressionISOAldh2 (Mus musculus)6480464CTDHydrogen Peroxide results in increased expression of ALDH2 mRNAPMID:31870920
Aldh2increases expressionISOALDH2 (Homo sapiens)6480464CTDHydrogen Peroxide results in increased expression of ALDH2 proteinPMID:35227738
Aldh2multiple interactionsISOAldh2 (Mus musculus)6480464CTDHydrogen Peroxide results in decreased expression of and results in decreased activity of ALDH2 proteinPMID:31870920
Aldh2multiple interactionsISOALDH2 (Homo sapiens)6480464CTDNFE2L2 protein affects the reaction [Hydrogen Peroxide results in increased expression of ALDH2 protein]PMID:35227738
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