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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732909
Species: Homo sapiens
RGD Object: Gene
Symbol: AKT1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:136004
Term: linsidomine
Definition: null
Chemical ID: MESH:C002385
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AKT1increases metabolic processingISOAkt1 (Mus musculus)6480464CTDlinsidomine results in increased metabolism of AKT1 proteinPMID:19682478
AKT1increases phosphorylationISOAkt1 (Rattus norvegicus)6480464CTDlinsidomine results in increased phosphorylation of AKT1 proteinPMID:17302912
AKT1multiple interactionsISOAkt1 (Rattus norvegicus)6480464CTDwortmannin inhibits the reaction [linsidomine results in increased phosphorylation of AKT1 protein]PMID:17302912
AKT1multiple interactionsISOAkt1 (Mus musculus)6480464CTDlinsidomine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]PMID:19682478
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