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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733096
Species: Mus musculus
RGD Object: Gene
Symbol: Hmbs
Name: hydroxymethylbilane synthase
Acc ID: CHEBI:102130
Term: sulfamerazine
Definition: A sulfonamide consisting of pyrimidine with a methyl substituent at the 4-position and a 4-aminobenzenesulfonamido group at the 2-position.
Chemical ID: MESH:D013416
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmbsdecreases activityISOHmbs (Rattus norvegicus)26923963RGDSulfamerazine decreases activity of purified Hmbs protein 
Hmbsincreases activityISOHmbs (Rattus norvegicus)4144820RGDSulfamerazine increases activity of purified Hmbs protein 
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