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GENE - TERM ANNOTATION REPORT

RGD ID: 8917295
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Cacna2d1
Name: calcium voltage-gated channel auxiliary subunit alpha2delta 1
Acc ID: DOID:9000184
Term: Ventricular Fibrillation
Definition: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
Definition Source(s): MESH:D014693
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cacna2d1 ISOCACNA2D1 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Ventricular fibrillationPMID:20817017 PMID:25527503 PMID:25741868 PMID:28492532
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