Cacna2d1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1) - Rat Genome Database

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Gene: Cacna2d1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1) Chinchilla lanigera
Analyze
Symbol: Cacna2d1
Name: calcium voltage-gated channel auxiliary subunit alpha2delta 1
RGD ID: 8917295
Description: ENCODES a protein that exhibits voltage-gated calcium channel activity (ortholog); voltage-gated calcium channel activity involved in bundle of His cell action potential (ortholog); INVOLVED IN calcium ion transmembrane transport (ortholog); calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); calcium ion transport (ortholog); ASSOCIATED WITH brain infarction (ortholog); breast carcinoma (ortholog); Brugada syndrome (ortholog); FOUND IN glutamatergic synapse (ortholog); L-type voltage-gated calcium channel complex (ortholog); neuronal dense core vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calcium channel, voltage-dependent, alpha 2/delta subunit 1; voltage-dependent calcium channel subunit alpha-2/delta-1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554103,619,740 - 3,964,239 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554103,544,398 - 3,963,582 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Cacna2d1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554103,619,740 - 3,964,239 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554103,544,398 - 3,963,582 (+)NCBIChiLan1.0ChiLan1.0
CACNA2D1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38781,946,444 - 82,443,956 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl781,946,444 - 82,443,956 (-)EnsemblGRCh38hg38GRCh38
GRCh37781,575,760 - 82,073,272 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36781,417,354 - 81,910,967 (-)NCBINCBI36Build 36hg18NCBI36
Build 34781,224,068 - 81,717,682NCBI
Celera776,279,569 - 76,773,517 (-)NCBICelera
Cytogenetic Map7q21.11NCBI
HuRef776,182,274 - 76,676,613 (-)NCBIHuRef
CHM1_1781,509,503 - 82,003,079 (-)NCBICHM1_1
T2T-CHM13v2.0783,197,632 - 83,695,210 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2780,910,288 - 81,405,123 (-)NCBI
Cacna2d1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39516,139,390 - 16,579,509 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl516,139,786 - 16,579,502 (+)EnsemblGRCm39 Ensembl
GRCm38515,934,264 - 16,374,511 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl515,934,691 - 16,374,511 (+)EnsemblGRCm38mm10GRCm38
MGSCv37515,440,509 - 15,880,329 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36515,446,612 - 15,882,875 (+)NCBIMGSCv36mm8
Celera512,936,968 - 13,372,202 (+)NCBICelera
Cytogenetic Map5A2- A3NCBI
cM Map56.56NCBI
Cacna2d1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8419,902,324 - 20,330,287 (-)NCBIGRCr8
mRatBN7.2418,950,611 - 19,374,969 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl418,951,002 - 19,374,969 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx424,107,697 - 24,535,090 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0419,924,586 - 20,351,968 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0418,305,637 - 18,733,033 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0415,706,974 - 16,130,848 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl415,710,417 - 16,130,848 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0415,681,399 - 16,105,483 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4415,139,881 - 15,566,740 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1415,169,848 - 15,566,733 (-)NCBI
Celera414,480,196 - 14,898,934 (-)NCBICelera
Cytogenetic Map4q12NCBI
CACNA2D1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2699,798,532 - 100,295,629 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17148,063,168 - 148,557,074 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0773,917,439 - 74,410,627 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1787,575,054 - 88,068,480 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl787,579,004 - 88,068,482 (-)Ensemblpanpan1.1panPan2
CACNA2D1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11821,561,091 - 21,949,970 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1821,564,676 - 21,949,544 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1821,233,630 - 21,714,674 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01822,009,947 - 22,485,359 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1822,009,954 - 22,485,691 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11821,646,522 - 22,121,006 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01821,182,147 - 21,656,514 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01821,836,185 - 22,311,929 (-)NCBIUU_Cfam_GSD_1.0
Cacna2d1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511863,375,924 - 63,825,676 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936734581,538 - 1,027,018 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936734577,656 - 1,027,412 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CACNA2D1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl997,781,090 - 98,266,969 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1997,781,057 - 98,265,925 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29108,068,038 - 108,554,997 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CACNA2D1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12166,449,154 - 66,937,643 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2166,770,578 - 66,934,898 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604237,008,715 - 37,508,631 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cacna2d1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473930,436,568 - 30,864,468 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473930,436,662 - 30,864,482 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000008951   ⟹   ENSCLAP00000008823
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554103,619,740 - 3,964,239 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000008952   ⟹   ENSCLAP00000008824
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554103,619,740 - 3,964,239 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000008953   ⟹   ENSCLAP00000008825
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554103,764,712 - 3,959,740 (+)Ensembl
RefSeq Acc Id: XM_005377191   ⟹   XP_005377248
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554103,544,398 - 3,963,582 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013510508   ⟹   XP_013365962
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554103,544,398 - 3,963,582 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013510509   ⟹   XP_013365963
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554103,544,398 - 3,963,582 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013510510   ⟹   XP_013365964
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554103,544,398 - 3,963,582 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005377248   ⟸   XM_005377191
- Peptide Label: isoform X3
- UniProtKB: A0A8C2V2F3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013365962   ⟸   XM_013510508
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V7V1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013365963   ⟸   XM_013510509
- Peptide Label: isoform X2
- UniProtKB: A0A8C2V7V1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013365964   ⟸   XM_013510510
- Peptide Label: isoform X4
- UniProtKB: A0A8C2V2F3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000008824   ⟸   ENSCLAT00000008952
RefSeq Acc Id: ENSCLAP00000008825   ⟸   ENSCLAT00000008953
RefSeq Acc Id: ENSCLAP00000008823   ⟸   ENSCLAT00000008951
Protein Domains
VWFA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006166 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000008951 ENTREZGENE
  ENSCLAT00000008951.1 UniProtKB/TrEMBL
  ENSCLAT00000008952 ENTREZGENE
  ENSCLAT00000008952.1 UniProtKB/TrEMBL
  ENSCLAT00000008953.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/TrEMBL
  PAS domain UniProtKB/TrEMBL
InterPro VDCC_a2/dsu UniProtKB/TrEMBL
  VWA_N UniProtKB/TrEMBL
  VWF_A UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
NCBI Gene Cacna2d1 ENTREZGENE
PANTHER VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 UniProtKB/TrEMBL
  VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED UniProtKB/TrEMBL
Pfam VGCC_alpha2 UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
  VWA_N UniProtKB/TrEMBL
PROSITE VWFA UniProtKB/TrEMBL
SMART VWA UniProtKB/TrEMBL
Superfamily-SCOP SSF53300 UniProtKB/TrEMBL
UniProt A0A8C2V2F3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2V4V8_CHILA UniProtKB/TrEMBL
  A0A8C2V7V1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Cacna2d1  calcium voltage-gated channel auxiliary subunit alpha2delta 1    calcium channel, voltage-dependent, alpha 2/delta subunit 1  Symbol and/or name change 5135510 APPROVED