GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pkm | increases uptake | ISO | PKM (Homo sapiens) | 6480464 | CTD | PKM protein results in increased uptake of Glucose | PMID:22574221 | Pkm | multiple interactions | ISO | PKM (Homo sapiens) | 6480464 | CTD | Fulvestrant inhibits the reaction [Glucose promotes the reaction [Estradiol results in increased phosphorylation of PKM protein]]; Glucose affects the reaction [Fusaric Acid results in increased expression of PKM mRNA]; Glucose affects the reaction [Fusaric Acid results in increased expression of PKM protein]; Glucose deficiency promotes the reaction [SAICAR binds to and results in increased activity of PKM protein]; Glucose promotes the reaction [Estradiol results in increased phosphorylation of PKM protein] | PMID:23086999 PMID:31654802 PMID:32078667 | | ||||||||||||||||||||||
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