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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736581
Species: Mus musculus
RGD Object: Gene
Symbol: Zfp36l1
Name: zinc finger protein 36, C3H type-like 1
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Zfp36l1affects expressionISOZfp36l1 (Rattus norvegicus)6480464CTDEstradiol affects the expression of ZFP36L1 mRNAPMID:32145629
Zfp36l1decreases expressionISOZFP36L1 (Homo sapiens)6480464CTDEstradiol results in decreased expression of ZFP36L1 mRNAPMID:16474171 PMID:19167446 PMID:20106945
Zfp36l1multiple interactionsISOZFP36L1 (Homo sapiens)6480464CTD[Dexamethasone co-treated with Estradiol] results in increased expression of ZFP36L1 mRNA; [Estradiol binds to ESR2 protein] which results in decreased expression of ZFP36L1 mRNA; [Estradiol co-treated with TGFB1 protein] results in increased expression of ZFP36L1 mRNA; [Medroxyprogesterone Acetate co-treated with Estradiol] results in increased expression of ZFP36L1 mRNA; [Promegestone co-treated with Estradiol] results in increased expression of ZFP36L1 mRNAPMID:19146866 PMID:20404318 PMID:30165855
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