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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736559
Species: Homo sapiens
RGD Object: Gene
Symbol: ESR1
Name: estrogen receptor 1
Acc ID: CHEBI:39096
Term: alpha-hexachlorocyclohexane
Definition: A hexachlorocyclohexane that has formula C6H6Cl6.
Chemical ID: MESH:C040534
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ESR1increases activityEXP 6480464CTDalpha-hexachlorocyclohexane results in increased activity of ESR1 proteinPMID:26022396
ESR1multiple interactionsISOEsr1 (Rattus norvegicus)6480464CTDalpha-hexachlorocyclohexane inhibits the reaction [Estradiol binds to ESR1 protein]PMID:10580743
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