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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735908
Species: Mus musculus
RGD Object: Gene
Symbol: Chrna2
Name: cholinergic receptor nicotinic alpha 2 subunit
Acc ID: CHEBI:9774
Term: tubocurarine
Definition: A benzylisoquinoline alkaloid muscle relaxant which constitutes the active component of curare.
Chemical ID: MESH:D014403
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrna2multiple interactionsISOChrna2 (Rattus norvegicus)6480464CTDTubocurarine inhibits the reaction [Acetylcholine binds to and results in increased activity of [CHRNB2 protein binds to CHRNA2 protein]]; Tubocurarine promotes the reaction [Acetylcholine binds to and results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]]PMID:7808438
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