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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735547
Species: Homo sapiens
RGD Object: Gene
Symbol: MBL2
Name: mannose binding lectin 2
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MBL2increases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of MBL2 mRNAPMID:25812627
MBL2decreases expressionISOMbl2 (Rattus norvegicus)6480464CTDperfluorooctanoic acid results in decreased expression of MBL2 mRNAPMID:19162173
MBL2decreases expressionISOMbl2 (Mus musculus)6480464CTDperfluorooctanoic acid results in decreased expression of MBL2 mRNAPMID:18467677 PMID:19429403 PMID:20936131
MBL2multiple interactionsISOMbl2 (Mus musculus)6480464CTDPPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of MBL2 mRNA]PMID:18467677
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