GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | XRCC1 | increases response to substance | EXP | | 6480464 | CTD | XRCC1 gene SNP results in increased susceptibility to Vinyl Chloride | PMID:17555083 PMID:18420361 PMID:20100738 | XRCC1 | multiple interactions | EXP | | 6480464 | CTD | GSTM1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]; GSTT1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]; XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene] | PMID:12010862 PMID:14602524 PMID:16097394 PMID:16881598 | XRCC1 | decreases expression | ISO | Xrcc1 (Rattus norvegicus) | 6480464 | CTD | Vinyl Chloride results in decreased expression of XRCC1 protein | PMID:15256147 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |