GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | AKT1 | multiple interactions | EXP | | 6480464 | CTD | [nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of AKT1 protein | PMID:30724446 | AKT1 | multiple interactions | ISO | Akt1 (Mus musculus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of AKT1 mRNA]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of AKT1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased phosphorylation of AKT1 protein]; [nickel chloride results in increased abundance of Nickel] which results in decreased expression of AKT1 mRNA; [nickel chloride results in increased abundance of Nickel] which results in decreased phosphorylation of AKT1 protein; Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased expression of AKT1 mRNA]; Melatonin inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in decreased phosphorylation of AKT1 protein]; Nickel promotes the reaction [Particulate Matter results in decreased phosphorylation of AKT1 protein] | PMID:23788629 PMID:35568058 | | ||||||||||||||||||||||
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