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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731555
Species: Mus musculus
RGD Object: Gene
Symbol: Gck
Name: glucokinase
Acc ID: CHEBI:50686
Term: atorvastatin calcium
Definition: An organic calcium salt composed of calcium cations and atorvastatin anions in a 1:2 ratio.
Chemical ID: MESH:D000069059
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gckdecreases expressionISOGck (Rattus norvegicus)6480464CTDAtorvastatin results in decreased expression of GCK proteinPMID:26616219
Gckdecreases expressionISOGCK (Homo sapiens)6480464CTDAtorvastatin results in decreased expression of GCK proteinPMID:26616219
Gckmultiple interactionsISOGCK (Homo sapiens)6480464CTDNR1I2 protein promotes the reaction [Atorvastatin results in decreased expression of GCK protein]PMID:26616219
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