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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731474
Species: Mus musculus
RGD Object: Gene
Symbol: Hmgcs1
Name: 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmgcs1increases expressionEXP 6480464CTDEthanol results in increased expression of HMGCS1 mRNAPMID:21955143
Hmgcs1multiple interactionsEXP 6480464CTDEthanol affects the expression of and affects the splicing of HMGCS1 mRNAPMID:30319688
Hmgcs1multiple interactionsISOHmgcs1 (Rattus norvegicus)6480464CTD[Fish Oils co-treated with Ethanol] results in increased expression of HMGCS1 mRNAPMID:17347304
Hmgcs1multiple interactionsISOHMGCS1 (Homo sapiens)6480464CTD[[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of HMGCS1 mRNAPMID:29432896
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