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GENE - TERM ANNOTATION REPORT

RGD ID: 731006
Species: Homo sapiens
RGD Object: Gene
Symbol: PTGS2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: DOID:9005372
Term: Inflammation
Definition: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
Definition Source(s): MESH:D007249
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTGS2 ISOPtgs2 (Rattus norvegicus)2300281RGDassociated with Cholestasis 
PTGS2 ISOPtgs2 (Rattus norvegicus)2300287RGDassociated with Ileus 
PTGS2 ISOPtgs2 (Rattus norvegicus) or Ptgs2 (Mus musculus)1642601RGD  
PTGS2 EXP 11554173CTDCTD Direct Evidence: marker/mechanismPMID:11094054 PMID:11321505 PMID:19084589
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