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GENE - TERM ANNOTATION REPORT

RGD ID: 731006
Species: Homo sapiens
RGD Object: Gene
Symbol: PTGS2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: DOID:9000998
Term: Brain Injuries
Definition: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
Definition Source(s): MESH:D001930
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTGS2 ISOPtgs2 (Rattus norvegicus)5508191RGD  
PTGS2 ISOPtgs2 (Mus musculus)5688162RGD  
PTGS2 EXP 11554173CTDCTD Direct Evidence: marker/mechanismPMID:12410334 PMID:20810888 PMID:21549006
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