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GENE - TERM ANNOTATION REPORT

RGD ID: 731006
Species: Homo sapiens
RGD Object: Gene
Symbol: PTGS2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: DOID:2384
Term: Wernicke encephalopathy
Definition: A brain disease that is characterized by the presence of neurological symptoms of ophthalmoplegia, ataxia, and confusion caused by biochemical lesions of the central nervous system after exhaustion of B-vitamin reserves, in particular thiamine (vitamin B1). (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Wernicke%27s_encephalopathy "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTGS2 ISOPtgs2 (Rattus norvegicus)2300278RGDmRNA, protein:increased expression:medial thalamic group, inferior colliculus, neuron 
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