GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PTGS2 | increases expression | EXP | | 6480464 | CTD | pirinixic acid results in increased expression of PTGS2 mRNA; pirinixic acid results in increased expression of PTGS2 protein | PMID:11840453 | PTGS2 | multiple interactions | EXP | | 6480464 | CTD | nimesulide inhibits the reaction [pirinixic acid promotes the reaction [PPARA protein results in increased expression of PTGS2 mRNA]]; nimesulide inhibits the reaction [pirinixic acid promotes the reaction [PPARG protein results in increased expression of PTGS2 mRNA]]; nimesulide inhibits the reaction [pirinixic acid results in increased expression of PTGS2 mRNA]; nimesulide inhibits the reaction [pirinixic acid results in increased expression of PTGS2 protein]; pirinixic acid promotes the reaction [PPARA protein results in increased expression of PTGS2 mRNA]; pirinixic acid promotes the reaction [PPARG protein results in increased expression of PTGS2 mRNA] | PMID:11840453 | PTGS2 | increases expression | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | pirinixic acid results in increased expression of PTGS2 mRNA; pirinixic acid results in increased expression of PTGS2 protein | PMID:9013627 | PTGS2 | multiple interactions | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | Dexamethasone inhibits the reaction [pirinixic acid results in increased expression of PTGS2 mRNA]; pirinixic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] | PMID:21300114 PMID:9013627 | | ||||||||||||||||||||||
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