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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731006
Species: Homo sapiens
RGD Object: Gene
Symbol: PTGS2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:28955
Term: 2-methoxy-17beta-estradiol
Definition: A 17beta-hydroxy steroid, being 17beta-estradiol methoxylated at C-2.
Chemical ID: MESH:C022830
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTGS2multiple interactionsEXP 6480464CTD2-Methoxyestradiol inhibits the reaction [cobaltous chloride results in increased expression of PTGS2 mRNA]; 2-Methoxyestradiol inhibits the reaction [cobaltous chloride results in increased expression of PTGS2 protein]PMID:28624453
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