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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731006
Species: Homo sapiens
RGD Object: Gene
Symbol: PTGS2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:28260
Term: galactose
Definition: An aldohexose that is the C-4 epimer of glucose.
Chemical ID: MESH:D005690
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTGS2increases expressionISOPtgs2 (Mus musculus)6480464CTDGalactose results in increased expression of PTGS2 mRNAPMID:22687555 PMID:28974442
PTGS2multiple interactionsISOPtgs2 (Mus musculus)6480464CTDGalactose results in increased expression of and results in increased activity of PTGS2 protein; lycopene inhibits the reaction [Galactose results in increased expression of PTGS2 mRNA]; protocatechuic acid inhibits the reaction [Galactose results in increased expression of PTGS2 mRNA]; protocatechuic acid inhibits the reaction [Galactose results in increased expression of PTGS2 protein]PMID:22687555 PMID:28974442
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