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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731006
Species: Homo sapiens
RGD Object: Gene
Symbol: PTGS2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:27757
Term: 4-chlorobiphenyl
Definition: A monochlorobiphenyl carrying a chloro substituent at position 4.
Chemical ID: MESH:C006983
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTGS2increases oxidationEXP 6480464CTDPTGS2 protein results in increased oxidation of 4-chlorobiphenyl metabolitePMID:19105592
PTGS2multiple interactionsEXP 6480464CTD[PTGS2 protein results in increased oxidation of 4-chlorobiphenyl metabolite] which results in increased chemical synthesis of QuinonesPMID:19105592
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